Diplomatic efforts between the United States and Iran center on resolving the disposition of Tehran’s remaining highly enriched uranium stockpile, estimated by the IAEA at over 200 kilograms of material enriched to 60 percent prior to 2025 strikes. The June 2026 Islamabad Memorandum outlined IAEA-supervised on-site down-blending as a minimum approach during a 60-day negotiation window, while recent October-November draft frameworks propose transfer to a third country or further reduction in exchange for sanctions relief and reopening the Strait of Hormuz. Iran has rejected any removal of the material, describing it as a national asset, and conditioned further talks on seven demands including asset releases. Ongoing Doha-mediated discussions and IAEA access limitations continue to shape verification challenges, with no confirmed transfer or acquisition by the United States as of early November 2026.