Taylor Swift’s “Patient Zero,” released September 25 as the lead single from the four-track *The Life of a Showgirl: The Encore* expanded edition, enters its first tracking week with outsized momentum from her record-shattering 2025 album. The track posted over 13.7 million Spotify streams on day one alone, claiming the year’s highest single-day mark for a female artist, fueled by Swifties’ rapid mobilization, limited-edition CD variants, and Max Martin–Shellback production. The September 27 MTV VMAs premiere of the cinematic video starring Dakota Johnson and Colin Farrell, plus Swift’s Artist Director Honors, added immediate visibility. Traders are weighing these factors against the original album’s 681 million first-week streams and prior single benchmarks exceeding 128 million when assessing thresholds like 50–100 million global streams through October 1.